DORINA STOICANESCU
Medical Genetics Department, University of Medicine and Pharmacy “Victor Babes” Timisoara, Romania
Multiple minor congenital anomalies in autism
ABSTRACT
The frequency of minor congenital anomalies and the mean number of these anomalies/person was examined in 76 patients with autism spectrum disorders and in unrelated control subjects matched by age and sex. The frequency of minor anomalies was not significantly different in the two groups, 14.47% in autistic children and teenagers, compared to 14.80% in healthy controls. The mean number of minor congenital anomalies was significantly higher in the autistic group, 3±0.70 minor anomalies/patient, compared to 1.43±0.36 minor subjects had three or more minor anomalies. These results support the idea that minor anomalies, especially multiple ones may represent markers of early prenatal factors that contribute to the adverse outcome.
Medical Genetics Department, University of Medicine and Pharmacy “Victor Babes” Timisoara, Romania
Multiple minor congenital anomalies in autism
ABSTRACT
The frequency of minor congenital anomalies and the mean number of these anomalies/person was examined in 76 patients with autism spectrum disorders and in unrelated control subjects matched by age and sex. The frequency of minor anomalies was not significantly different in the two groups, 14.47% in autistic children and teenagers, compared to 14.80% in healthy controls. The mean number of minor congenital anomalies was significantly higher in the autistic group, 3±0.70 minor anomalies/patient, compared to 1.43±0.36 minor subjects had three or more minor anomalies. These results support the idea that minor anomalies, especially multiple ones may represent markers of early prenatal factors that contribute to the adverse outcome.
KEY WORDS multiple minor congenital anomalies, autism, predictive value