S. C. STOIAN(1),.NICOLETA PĂTREANĂ(2), DIANA PAVLOVA(1), CRISTIANA SIMIONESCU(2)

(1) Disciplina Obstetrică Ginecologie, UMF Craiova ; (2) Disciplina Anatomie Patologică , UMF Craiova

REZUMAT

Va prezentăm un studiu histopatologic retrospectiv care a cuprins un număr de 20 carcinoame endometriale, internate si operate in Clinicile de Ginecologie ale Spitalului de Urgenta Craiova. La cazurile analizate s-au urmărit: vârsta medie de diagnosticare, gradingul tumoral, gradul de penetrare miometrială si existenţa invaziei locale sau locoregionale.Corelarea gradingului de diferenţiere cu stadiul progresiei tumorale a permis observarea faptului că în timp ce adenocarcinoamele endometroide bine diferenţiate invazive au fost limitate la nivelul corpului uterin, cele moderat şi slab diferenţiate pe lângă invazie miometrială profundă au asociat in unele cazuri invazie cervicală şi metastaze în structuri situate la distanţă.

CUVINTE CHEIE carcinoame endometroide, histopatologie, corelaţii

Hystopathological aspects of the endometrial carcinomas in correlation with the tumoral grading and the invasiveness

ABSTRACT

We present you a retrospective hystopathological study which comprised a number of 20 endometrial carcinomas, hospitalised and operated in the Gynecology Clinics of the Emergency Hospital of Craiova. We have analysed the following aspects of the previous mentioned cases: the average age for diagnosis, the tumoral grading, the miometrial penetration degree and the existence of the local or loco-regional invasion. The correlation of the differentiation level with that of the tumoral progression allowed us to observe the fact that while the well differentiated invasive endometroide adenocarcinomas were limited at the level of the uterine body, the moderated and the poorly differentiated ones associated, in some cases, beside cervical invasion and metastasis in structures situated at some distance, a profound miometrial invasion.